Temporal 3D Lagrangian strain from 2D slice-followed cine DENSE MRI

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Temporal 3D Lagrangian strain from 2D slice-followed cine DENSE MRI.

A quantitative analysis of myocardial mechanics is fundamental to the understanding of cardiac function, diagnosis of heart disease and assessment of therapeutic intervention. In clinical practice, most cardiac imaging analyses are performed in 2D because of the limited scan time available. However, the obtained information from a 2D measurement is limited. This study presents a method to obtai...

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........................................................................................................................ II Acknowledgements ...................................................................................................... III Table of

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Background 3D cine displacement encoding with stimulated echoes (DENSE) directly encodes tissue displacement into MR phase data, providing a comprehensive 3D view of cardiac motion and strain. Unfortunately, 3D cine DENSE motion analysis presently requires manually delineated anatomy. An automated analysis would reduce interobserver variability, improve measurement throughput, and simplify data...

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Introduction Cine DENSE (Displacement Encoding with Stimulated Echoes) MRI acquires a temporal sequence of images where the phase of each image is encoded for tissue displacement. More specifically, the phase of the DENSE stimulated-echo signal is given by θ = keΔx, where Δx is the tissue displacement and ke is the userspecified displacement-encoding frequency (a parameter analagous to the “ven...

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ژورنال

عنوان ژورنال: Clinical Physiology and Functional Imaging

سال: 2011

ISSN: 1475-0961

DOI: 10.1111/j.1475-097x.2011.01068.x